Programme
For PDF Download please click here. (last update 05/04/2013)
| Wednesday, April 3rd | |||
| Topic | Time | Speaker | Title |
| 18:00 | Welcome reception | ||
| 19:00 | Welcome | ||
| (1) Protein Synthesis | 19:10 | S. Kent | Through the Looking Glass: Racemic Protein Crystallography & D-Protein Therapeutics |
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| Thursday, April 4th | |||
| Topic | Time | Speaker | Title |
| (1) Protein Synthesis | 09:00 | P. Dawson | Challenges in chemoselective amide bond formation |
| 09:30 | J. Bode | Chemical Protein Synthesis with the KAHA Ligation | |
| 10:00 | A. Brik | Studying and Targeting Deubiquitinases Enabled by Chemical Protein Synthesis | |
| 10:30 | Coffee Break | ||
| 11:15 | O. Melnyk | Bis(2-sulfanylethyl)amido native peptide ligation and the total synthesis of hepatocyte growth factor subdomains: the challenge of understanding MET tyrosine kinase receptor activation | |
| 11:45 | L. Liu | Examining the Use of Peptide Hydrazides for Protein Chemical Synthesis | |
| 12:15 | C. Hackenberger | When Staudinger meets Huisgen: Chemical Approaches to Functional Proteins | |
| 12:45 | Lunch (in house) | ||
| 14:00 | Short Poster Talks (10 min each) Please see list below | ||
| 15:30 | Coffee Break | ||
| 16:15 | O. Seitz | Templated native chemical ligation | |
| (2) Protein Chemistry | 16:45 | E.J. Petersson | Thioamides: Minimalist chromophores for monitoring protein dynamics |
| 17:15 | E. Lemke | Genetically encoded tools to decipher protein plasticity at the single molecule level | |
| 17:45 | Y. Wu | Probing protein function by chemical modification | |
| 18:15 | Poster Session (including drinks) | ||
| 20:00 | Dinner (on your own) | ||
| Friday, April 5th | |||
| Topic | Time | Speaker | Title |
| (3) Peptide / Protein drugs | 09:00 | A. Beck-Sickinger | Chemical modification of proteins for efficient drug release and novel biomaterials |
| 09:30 | A. Karlstrom | Affibody molecules for diagnostic applications | |
| 10:00 | D. Neri | Tumor targeting: from armed antibodies to small targeted cytotoxics | |
| 10:30 | Coffee Break | ||
| 11:15 | G. Dawson | Targeted Quantum Dot delivery of peptides and proteins into cells | |
| 11:45 | D. Schwarzer | Evolved sortase A mutants for peptide and protein chemistry | |
| 12:45 | Lunch (in house) | ||
| (4) Glycoprotein | 14:30 | Y Kajihara | Chemical Synthesis of Homogeneous Erythropoietin bearing M9-highmannose type oligosaccharide |
| 15:00 | B. Davis | Sugars & Proteins | |
| 15:30 | C. Unverzagt | Semisynthesis of N-glycoproteins by convergent methods | |
| 16:00 | Coffee Break | ||
| 16:30 | D. Varon Silva | Glycosylphosphatidylinositol Anchors: A Complex Bridge Between Proteins and Membranes | |
| 17:00 | R. Payne | Synthesis of Glycopeptide and Glycoproteins via Ligation Chemistry | |
| (5) Protein Function | 17:30 | C. Becker | Modified Silaffin Peptides – Understanding silica precipitation activity and biotechnological applications |
| 18:00 | M. Engelhard | Chemical synthesis of membrane proteins: Challenges and solutions | |
| 18:30 | Dinner (together) | Melker Stiftskeller, Schottengasse 3, 1010 Wien | |
| Saturday, April 6th | |||
| Topic | Time | Speaker | Title |
| (5) Protein Function | 09:00 | D. Trauner | Enzymes and GPCRs: The Age of Enlightenment |
| 09:30 | H. Lashuel | Dissecting role of post-translational modifications in the pathogenesis of neurodegenerative disease using chemical protein synthesis and semisynthetic strategies | |
| 10:00 | H. Mootz | Chemical conjugation of proteins with ubiquitin-like modifiers | |
| 10:30 | Coffee Break | ||
| 11:15 | S. Horne | Sequence-Based Strategies for the Mimicry of Protein Tertiary Folding | |
| 11:45 | F. Bordusa | Engineering Trypsin for Peptide and Protein Semisynthesis | |
| 12:15 | Lunch & Departure | ||
Short Poster Talks: (10 min each)
| Wolfgang Fischle | Probing post-translational histone modifications using in vitro approaches |
| Stijn Agten | Chemoselective reactions in proteins and peptides using an optimized oxime strategy: the demise of levulinic acid. |
| Vincent Aucagne | Simplifiying Chemical Protein Synthesis: Iterative Solid-Supported Peptidomimetic Ligations with Concomitant Purifications |
| Eric R. Strieter | Chemical tools for studying ubiquitin signaling |
| Norman Metanis | Using Selenocysteine Substitutions to Steer Oxidative Protein Folding |
| Carsten Schultz | New tools to cross-link proteins in intact cells |
| Verena Schart | Synthesis of Alkene-derivatized Fucose – Toward the Detection of Glycoproteins |
| Christian Gruber | Pharmacological applications of natural peptide libraries |
| Cornelia Panse | Photocleavable auxiliary in PNA base pairing mediated ligation |
